|
|
|
Surfacine |
Medical
Grade Disinfectant |
Antimicrobial
Agent Compounded Into Bulk Polymer |
Silver
Deposited On Surface |
|
Mode
of Application |
|
Molecularly
designed surface treatment |
Floods surface |
Antimicrobial agent
is compounded with polymer |
Metallic silver
surface film by vacuum deposition, ion sputtering, etc. |
|
Mode
of Action |
|
Surface
contact only, microbial surface contact exposes organism to antimicrobial
agent |
Chemically compromises
micro-organism depending upon nature of disinfectant |
Active agent diffuses
to the surface where it may be leached away by contact with liquids,
other surfaces, etc. |
Surface contact
with micro-organisms, as well as significant slow leaching into
solution |
|
Bio
Availability |
|
Very
high for surface contact, none in solution |
High while immersed,
none thereafter |
High on fresh surfaces,
low on surfaces in contact with clean solutions |
High for surface
contacts, moderate in bulk of solution |
|
Duration
of Activity |
|
Long
term |
Short term. Active
only while surface is wetted with agent and agent is not chemically
exhausted |
Depending on compatibility
of active agent with polymer. Short to medium term |
Long term |
|
Reservoir
Capacity |
|
High |
None |
Depending on compatibility
of active agent with polymer. Low to high |
High |
|
Leaching
into Solution |
|
Less
than 50 ppb, often below 10 ppb |
Depending on the
disinfectant, often 5 to 10 ppm or higher |
Depending on solution
contact time with surface. Often exceeds 100 ppm |
Greater than 5
ppm, depending on the contact solution |
|
Time
to Kill Micro-organisms |
|
Moderate |
Fast |
Slow to moderate
depending on surface concentration |
Moderate |
|
Spores
Activity |
|
Low |
Moderate |
Low |
Low |
|
Virus
Activity |
|
Undetermined |
Depending on disinfectant |
Typically none |
None |
|
Toxicity
to Humans |
|
None |
High |
Depending on active
agent |
Low to none |
|
Sensitivity
to Surface Fouling |
|
High |
Low |
Low |
Moderate |
|
Vulnerability
to Crevices |
|
Low |
High |
Low |
Low |
|
Limitations |
|
Activity
will be reduced with surface fouling |
Must be applied
repeatedly, wetting all surfaces and crevices, and remaining
undiluted |
Activity related
to surface concentration and availability of leaching agent.
Appropriate to polymeric materials |
Microorganism may
either come into contact with surface or reside in a solution
that has been in contact with the surface |
|
Substrates |
|
Most |
Most (some surfaces
may be damaged by disinfectants) |
Polymeric |
Most |
|
Mechanical
Robustness |
|
Can
be engineered to meet requirements over wide range |
Not applicable |
Equivalent to properties
of base material |
Low |
|
Manufacturing
Compatibility |
|
Flexible
post-manufacturing process |
Not part of the
device |
Changes material's
manufacturing and mechanical properties |
Vacuum line-of-sight
deposition |
|
Cost
of disinfection activity |
|
Low
for long term protection |
High, assuming
repeated applications |
Generally low,
depending on agent |
High for long term
protection |